Denise Aberle

Denise Aberle


Professor, David Geffen School of Medicine


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Dr. Aberle is a professor of Radiology in the School of Medicine and professor of Bioengineering in the Henry Samueli School of Engineering and Applied Sciences. She is board-certified in Internal Medicine and Diagnostic Radiology. Dr. Aberle earned her MD degree in 1979 at the University of Kansas in Kansas City, KS and completed a residency in Internal Medicine at Boston University Medical School in 1982. She completed a residency in Diagnostic Radiology at UCLA in 1982, and subspecialty training in thoracic imaging at the University of California, San Francisco. She has been on faculty in Radiological Sciences since 1987, and was the Section Chief of Thoracic Imaging from 1988 to 2005. Dr. Aberle is the Vice Chair of Research in Radiological Sciences and a faculty member in the interdisciplinary Biomedical Physics and the Medical Imaging Informatics training programs, both sponsored by the National Institutes of Health. Dr. Aberle was the Principal Investigator of the ACRIN-NLST (American College of Radiology Imaging Network component of the National Lung Screening Trial). The NLST was an NCI-sponsored randomized trial that compared lung cancer mortality between low dose helical CT (LDCT)versus chest radiography for lung cancer screening. The trial observed a 20% lung cancer mortality reduction with LDCT, which has led to the endorsement of LDCT screening for lung cancer by multiple medical societies. Dr. Aberle's research centers on lung cancer screening | early diagnosis | prevention and screening implementation. Other interests include: oncologic imaging for response assessment; quantitative image analysis, and oncology informatics.