Joe joined the UCLA Engineering faculty in 1966, Medicine faculty in 1970, Computer Science faculty in 1982 and became chair of the undergrad Cybernetics Interdepartmental Program (IDP) in 1981. He Chairs the undergrad Computational & Systems Biology IDP, the Computational Systems Biology grad program in Computer Science, Co-Chairs the Biosystem Science and Engineering Major in the Biomedical Engineering graduate IDP and directs the UCLA Biocybernetics Research Laboratory.